Disease: Myelodysplasia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
WT1 P19544 WT1 transcription factor Nucleic acid binding 1.00 0.422 0.808
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
THPO P40225 thrombopoietin 0.20 0.513 0.692
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
TET2 Q6N021 tet methylcytosine dioxygenase 2 4.3E-54 0.458 0.808
TERT O14746 telomerase reverse transcriptase Enzyme 0.99 0.374 0.846
TBC1D9 Q6ZT07 TBC1 domain family member 9 Enzyme 2.8E-05 0.399 0.846
SLCO6A1 Q86UG4 solute carrier organic anion transporter family member 6A1 Transporter 2.9E-11 0.412 0.885
SF3B1 O75533 splicing factor 3b subunit 1 Nucleic acid binding 1.00 0.511 0.731
RUNX1T1 Q06455 RUNX1 partner transcriptional co-repressor 1 Transcription factor 0.98 0.530 0.808
RUNX1 Q01196 RUNX family transcription factor 1 Transcription factor 0.65 0.425 0.808
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923
PHF6 Q8IWS0 PHD finger protein 6 Nucleic acid binding 1.00 0.581 0.692
NUP98 P52948 nucleoporin 98 and 96 precursor Enzyme 1.00 0.532 0.577
NUP214 P35658 nucleoporin 214 Nucleic acid binding 5.5E-02 0.638 0.385
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
NPM1 P06748 nucleophosmin 1 Chaperone 1.00 0.464 0.846
NCAM1 P13591 neural cell adhesion molecule 1 1.00 0.415 0.885
MECOM Q03112 MDS1 and EVI1 complex locus 1.00 0.513 0.731
KMT2A Q03164 lysine methyltransferase 2A 1.00 0.410 0.885
KITLG P21583 KIT ligand 0.85 0.473 0.885
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808
IL3 P08700 interleukin 3 2.6E-09 0.489 0.731
IDH1 O75874 isocitrate dehydrogenase (NADP(+)) 1 2.6E-12 0.424 0.808
HPGDS O60760 hematopoietic prostaglandin D synthase 1.8E-06 0.388 0.923